News Hub | News Direct

A Company With Solutions Against Emerging COVID Variants And Other Viral Infections To Combat Future Pandemic Threats

NanoViricides, Inc.

By Ernest Dela Aglanu, Benzinga With the COVID pandemic still ongoing, having claimed more than 6.8 million lives from about 758 million cases and crippling the global economy, there are several reasons why drug research and development related to the COVID virus remains highly relevant and necessary. Ongoing drug development by companies such as NanoViricides Inc. (NYSEAMERICAN: NNVC) is vital because new variants of the virus keep emerging and viral infections, hospitalizations and deaths continue at a much greater rate than even pandemic influenza years despite the roll-out of vaccines from players like Novavax Inc. (NASDAQ: NVAX), Moderna Inc. (NASDAQ: MRNA), Oxford– AstraZeneca plc (LON: AZN), and Pfizer Inc. (NYSE: PFE)–BioNTech As new virus variants continue to develop, researchers must stay ahead of the curve to identify and combat them. Given the fast-evolving nature of the virus, early detection of these new variants is thought to be crucial in controlling their spread and preventing further outbreaks. However, with significantly reduced testing worldwide, it is now widely understood that a new damaging variant may not be readily identified before it spreads. Even after 3 years of pandemic, do we have effective drugs that could stop the next variant? Unfortunately, we don’t have even one safe and effective drug that does not come with a lot of limitations. This is why the need to treat current infections and also to better prepare for future pandemics has spurred a new wave of investment and interest in COVID research and development. NanoViricides has recently reported that it is very close to testing its drug candidate NV-CoV-2 to treat SARS-CoV-2 infection in human clinical trials. Thus the Company is nearing an inflection point in its lifecycle, with the first clinical trials of its unique and novel nanomedicines platform. Human clinical trials are now becoming imminent — NanoViricides will no longer be a R&D/Drug Discovery company, but will soon become a clinical-stage pharma company. Traders and investors are taking note of what could be a unique opportunity. NanoViricides, a growing innovator in nanomedicine and antiviral therapies, has been maturing its nanomedicine technology in developing drugs against many viruses for over 15 years, and their most recent developments could potentially prove to be market-disrupting with implications for treating dozens of viruses worldwide. All these years of research and development are coming together for NanoViricides, now, positioning it to potentially become a major player in the antivirals space. NanoViricides has reported: A platform technology that enables it to develop drugs rapidly against many viruses as shown with many candidates in pre-clinical studies against a number of viruses. Technology to make drugs that variants of the virus cannot escape because no matter how much the virus changes, it uses the same receptor, and this company’s technology for first-in-class drugs is based on making copies of that unique receptor. A novel mechanism of action, enabling first-in-class drugs against viruses. Technology to make broad-spectrum antiviral drugs. For example, the company has shown in preclinical studies that its COVID drug works against all the tested coronaviruses. The ability to manufacture first-in-class drugs at scale to make finished drug products for clinical trials of their lead candidate against COVID in its own cGMP compliant manufacturing facility. The COVID drug, NV-CoV-2, has been formulated and tested in the form of Oral Gummies, and also as Oral Syrup - to help COVID-positive patients, including children and older patients who need more accessible treatments. Read the latest report on NanoViricides here. Dosing And Effectiveness NV-CoV-2 Reportedly Superior An additional problem for current COVID cases is that available COVID drugs like remdesivir by Gilead (NASDAQ: GILD), molnupiravir by Merck (NYSE: MRK), and to a lesser extent, Paxlovid by Pfizer (NYSE: PFE) face the challenge of limited dosing for safety reasons — which is a part of why they have limited effectiveness and limitations on use — increasing dosage would not give increased benefit thus limiting the drugs’ capability. Unlike these drugs, the very high safety numbers that NV-CoV-2 has demonstrated in rat studies indicate that patients might be able to take more of the Company’s COVID drug to achieve greater effectiveness when their sickness is more severe. This is expected to be validated in imminent human clinical trials. Once NanoViricides proves that its COVID drug is safe in clinical trials, the company’s entire platform of nanotechnology would essentially be validated as being capable of developing safe drugs. Additionally, assuming NanoViricides demonstrates strong effectiveness of the COVID drug in clinical trials, similar to the strong effectiveness they have reported in their pre-clinical studies, that would validate the Company’s pre-clinical approach in studying effectiveness for developing clinical candidates, and will likely have strong positive implications for the other drug candidates in their pipeline too. As NanoViricides’ reported effective and safe solutions for battling against the COVID pandemic move into the clinic, heralding its official entry as a pharmaceutical drug maker, the story doesn’t stop there. Once the platform is proven, the Company could be well positioned to develop solutions to battle other current and future pandemics as well. The company has drugs nearing clinical stage for treating Shingles and Herpes Viruses (HSV-1 and HSV-2). And it says it will be forging ahead to further develop candidates to battle HIV, Ebola/Marburg, Monkeypox, and other viruses. With the global antiviral therapy market valued at $48.1 billion in 2018 and estimated to garner $79.8 billion by 2026, rising at a compound annual growth rate (CAGR) of 6.7% from 2019 to 2026, NanoViricides could be strategically placed to participate in such significant market size and growth while potentially revolutionize the industry with the Company’s unique biomimetic technology. Head to https://profiles.smallcapsdaily.com/nnvc/ to read more about NanoViricides’ technology. This article originally appeared on Benzinga here. About NanoViricides NanoViricides, Inc. (the "Company") (www.nanoviricides.com) is a development stage company that is creating special purpose nanomaterials for antiviral therapy. The Company's novel nanoviricide® class of drug candidates are designed to specifically attack enveloped virus particles and to dismantle them. Our lead drug candidate is NV-HHV-101 with its first indication as dermal topical cream for the treatment of shingles rash. In addition, we are developing a clinical candidate for the treatment of COVID-19 disease caused by SARS-CoV-2 coronavirus. The Company cannot project an exact date for filing an IND for this drug because of its dependence on a number of external collaborators and consultants.The Company is now working on tasks for completing an IND application. The Company is currently pursuing two separate drug candidates for the treatment of COVID-19 patients. NV-CoV-2 is our nanoviricide drug candidate that does not encapsulate Remdesivir. NV-CoV-2-R is our other drug candidate that is made up of NV-CoV-2 with Remdesivir encapsulated in it. The Company believes that since Remdesivir is already US FDA approved, our drug candidate encapsulating Remdesivir is likely to be an approvable drug, if safety is comparable. Remdesivir is developed by Gilead. The Company has developed both of its own drug candidates NV-CoV-2 and NV-CoV-2-R independently.The Company intends to re-engage into an IND application to the US FDA for NV-HHV-101 drug candidate for the treatment of shingles once its COVID-19 project moves into clinical trials, based on resources availability. The NV-HHV-101 program was slowed down because of the effects of recent COVID-19 restrictions, and re-prioritization for COVID-19 drug development work.The Company is also developing drugs against a number of viral diseases including oral and genital Herpes, viral diseases of the eye including EKC and herpes keratitis, H1N1 swine flu, H5N1 bird flu, seasonal Influenza, HIV, Hepatitis C, Rabies, Dengue fever, and Ebola virus, among others. NanoViricides' platform technology and programs are based on the TheraCour® nanomedicine technology of TheraCour, which TheraCour licenses from AllExcel. NanoViricides holds a worldwide exclusive perpetual license to this technology for several drugs with specific targeting mechanisms in perpetuity for the treatment of the following human viral diseases: Human Immunodeficiency Virus (HIV/AIDS), Hepatitis B Virus (HBV), Hepatitis C Virus (HCV), Rabies, Herpes Simplex Virus (HSV-1 and HSV-2), Varicella-Zoster Virus (VZV), Influenza and Asian Bird Flu Virus, Dengue viruses, Japanese Encephalitis virus, West Nile Virus, Ebola/Marburg viruses, and certain Coronaviruses. The Company intends to obtain a license for poxviruses if the initial research is successful. The Company's technology is based on broad, exclusive, sub-licensable, field licenses to drugs developed in these areas from TheraCour Pharma, Inc. The Company's business model is based on licensing technology from TheraCour Pharma Inc. for specific application verticals of specific viruses, as established at its foundation in 2005. This post contains sponsored advertising content. This content is for informational purposes only and not intended to be investing advice. Contact Details NanoViricides, Inc. +1 203-937-6137 info@nanoviricides.com Company Website http://www.nanoviricides.com

March 20, 2023 09:45 AM Eastern Daylight Time

Hong Kong Baptist University-led research unveils cell entry mechanism of SARS-CoV-2 and therapeutic target for COVID-19

Hong Kong Baptist University

HONG KONG SAR - Media OutReach - 20 March 2023 - A study led by scientists from Hong Kong Baptist University (HKBU) has identified a protease called MT1-MMP that is a major host factor behind the infectivity of the SARS-CoV-2 virus in the human body, which leads to the infection of COVID-19 and multi-organ failure. By applying a humanised antibody called 3A2 that can inhibit the activity of MT1-MMP, the viral load of infected mice was reduced by almost 90%. The research team also demonstrated that the protease is a potential therapeutic target for COVID-19. Dr Xavier Wong Hoi-leong, Assistant Professor, and Dr Guo Xuanming, researcher of the Teaching and Research Division of the School of Chinese Medicine, introduce the research findings on the cell entry mechanism of SARS-CoV-2 and therapeutic target for COVID-19. The research findings have been published in the internationally renowned scientific journal Nature Communications. ACE2 as a receptor for SARS-CoV-2 cell entry Vaccination can protect people against COVID-19 and its potential complications, but it is not always effective in individuals with weak immune systems, or against some COVID-19 variants of concern. Thus, the development of a more effective treatment for COVID-19 remains a huge challenge in the post-vaccine era. Understanding the cell entry mechanism of SARS-CoV-2 is vital to curb the spread of the virus, and it will also aid the search for new COVID-19 treatments. SARS-CoV-2 requires angiotensin-converting enzyme 2 (ACE2), a protein found on the membrane of human cells, as its receptor for cellular entry. Despite the lungs being the major organ affected by SARS-CoV-2 infection, only a small proportion of lung cells express ACE2. Previous studies found that the infection of organs with low levels of ACE2 expression by SARS-CoV-2 is made possible by a soluble form of ACE2. The soluble ACE2 binds with SARS-CoV-2, carries the virus to cells with low levels of ACE2 expression, and facilitates its entry into the cells. MT1-MMP mediates cell entry of SARS-CoV-2 A research team led by Dr Xavier Wong Hoi-leong, Assistant Professor of the Teaching and Research Division of the School of Chinese Medicine at HKBU, in collaboration with Dr Yuan Shuofeng, Assistant Professor of the Department of Microbiology at The University of Hong Kong, further studied how the physiological regulation of soluble ACE2 shedding contributes to the aetiology of COVID-19. The team found that SARS-CoV-2 infection leads to the increased activation of MT1-MMP, a protease crucial for many physiological processes. MT1-MMP mediates the release of soluble ACE2 from ACE2-expressing cells. This soluble ACE2 in turn binds to the spike proteins of SARS-CoV-2 and carries it to the uninfected cells with low levels of ACE2 expression. Notably, the team demonstrated that the introduction of human-soluble ACE2 enables SARS-CoV-2 to infect the lungs of a laboratory mouse strain (C57BL/6 mice) that is naturally insusceptible to SARS-CoV-2 infection due to the incompatibility of its mouse ACE2 and the viral spike proteins. The findings unveil the mechanism by which the virus hijacks host enzymes to enhance its infectivity, triggering multi-organ infections. Antibody 3A2 blocks MT1-MMP activity To study MT1-MMP's functions and how it affects viral infection, the researchers used human cells to create organoids, a 3D tissue structure grown in vitro to resemble and model different organs in the laboratory. They discovered that blocking MT1-MMP activity with the monoclonal antibody 3A2 effectively depleted soluble ACE2 levels and reduced the degree of infection of SARS-CoV-2 in human lung, heart and liver organoids by 60-80%. Consistent results were obtained using the original strain of SARS-CoV-2, as well as variants of concern, such as Delta and Omicron. The results demonstrate that MT1-MMP is a major host factor that mediates the cell entry of SARS-CoV-2, and that it is also a potential therapeutic target for COVID-19 drugs. The researchers further tested the effects of applying 3A2 in a mouse COVID-19 model. A group of 11 mice were treated with either 3A2 or vehicle controls. Older mice were used in the experiment as old age is a major risk factor for severe symptoms and mortality for COVID-19. The results show that 3A2 reduced the viral load of SARS-CoV-2 by almost 90% and dramatically alleviated lung tissue damage resulting from infection. MT1-MMP as a therapeutic target Dr Wong said: "Two major challenges when it comes to developing COVID-19 drugs are how to enhance treatment results for patients with weakened immune systems, and how to maintain the drugs' effectiveness across different viral strains. 3A2 has good potential to become an effective drug for curing COVID-19 because it antagonises the activity of MT1-MMP, instead of boosting the immunity of patients or acting directly on the virus. "Our previous studies have demonstrated that 3A2 also offers protection against obesity and diabetes, two major risk factors for severe symptoms and mortality for COVID-19. Therefore, 3A2 could be particularly suitable for high-risk groups, including older adults and people with metabolic disorders. It could also be effective against emerging coronaviruses in the future, because ACE2 is a doorway for many such viruses with similar cell entry mechanisms. Further research and experiments on 3A2 are required before it can be applied in humans." Contact Details Communication and Public Relations Office Christina Wu christinawu@hkbu.edu.hk

March 20, 2023 09:00 AM Eastern Daylight Time

Image

Kadimastem Earns FDA Approval of its IND Application For its US Multi-Site Phase IIa Clinical Trial of AstroRx® to Treat ALS

Kadimastem Ltd.

Kadimastem Ltd. (TASE: KDST), a clinical stage cell therapy company, developing and manufacturing "off-the-shelf" allogeneic cell products using its platform technology to develop treatments for different neurodegenerative diseases and a potential cure for diabetes, has received FDA clearance to commence a phase IIa clinical trial in the US according to the Investigational New Drug (IND) application that was submitted in February 2023. The trial will test its lead neurological cell therapy product AstroRx ® in repeated dosing of three-month intervals for the treatment of patients with ALS. The planned clinical trial follows a first in human phase I/IIa clinical trial previously conducted by the company in Israel, in which AstroRx® was injected into the spinal cord fluid using a standard lumbar puncture procedure. In this phase I/IIa clinical trial Kadimastem demonstrated a good safety profile and clinically meaningful decline in the disease progression during the first 3-months follow-up period. AstroRx® contains functional, healthy astrocytes (nervous system supporting cells) differentiated from human Embryonic Stem Cells (hESC) that aim to support the survival of diseased motor neurons through several mechanisms of action. The treatment’s goal is to nourish and support the malfunctioning motor neurons in the brain and spinal cord of patients suffering from Amyotrophic Lateral Sclerosis (ALS), to significantly slow the progression of the disease and improve the quality of life and life expectancy of the treated patients. Kadimastem CEO Asaf Shiloni said, “The FDA approval for this multi-site clinical trial is a major achievement for us and is a recognition of our professional, clinical and scientific abilities. I’d like to congratulate our dedicated team on this extremely important landmark, which is an enormous milestone that brings great hope for the future of the ALS patients as well as our supporters and investors.” Kadimastem Founder and Chief Scientific Officer Professor Michel Revel said, “The approval of submission of the IND to the FDA is a major achievement and moment of pride for me in the company that I have founded years ago, with an amazing team. It is very exciting, and we eagerly await to start this trial and wish to help ALS patients as soon as possible.” About AstroRx ® & ALS Kadimastem’s flagship product, AstroRx®, is a breakthrough technology that is comprised of a unique and large cell population of astrocytes derived from human pluripotent stem cells. The cells are intended to support the survival of motoneurons (neurons the control the motor-capability) in the central nervous system (CNS, brain and spinal cord). AstroRx® enables the transplantation of healthy astrocytes into the CNS of the ALS patient and an improvement in the protection of the motoneurons. In December 2020, Kadimastem announced the results Kadimastem (TASE:KDST) is a clinical stage biotechnology company, with a unique platform for cell therapy that enables the production of off-the-shelf cell-based products for the treatment of unmet medical needs. of the first of its kind, Phase I/IIa clinical trial, in which healthy and functioning astrocyte cells (AstroRx®) were injected into the spinal fluid of 10 ALS patients. Data showed that AstroRx® has the potential to slow the progression of ALS, as indicated by a clinical score called ALSFRS-R. Kadimastem plans to test repeated doses every three months of AstroRx® to achieve a continuous delay of the disease. This document may include forward-looking information as defined in the Securities Law, 5728 – 1968. Forward-looking information is uncertain and mostly is not under the Company's control and the realization or non-realization of forward-looking information will be affected, among other things, by the risk factors characterizing the Company's activity, as well as developments in the general environment and external factors affecting the Company's activity. The Company's results and achievements in the future may differ materially from any presented herein and the Company makes no undertaking to update or revise such projection or estimate and does not undertake to update this document. This document does not constitute a proposal to purchase the Company's securities or an invitation to receive such offers. Investment in securities in general and in the Company in particular bears risks. One should consider that past performance does not necessarily indicate performance in the future. Contact Details Kadimastem Sarah Bazak +972 73-797-1601 s.bazak@kadimastem.com GOTLIVE Media Group Lior Gottlieb +972 50-920-0194 lior@gotlive-ir.co.il Company Website https://www.kadimastem.com/

March 20, 2023 07:00 AM Eastern Daylight Time

AMERICAN DIVERSIFIED HOLDINGS CORP (OTC: ADHC) REACHES AGREEMENT FOR COMPREHENSIVE TRANSITION OF ALL BUSINESS OPERATIONS

American Diversified Holdings Corp.

McapMediaWire -- American Diversified Holdings Corporation (OTC: ADHC ) announced today that the Company has filed its quarterly financials ending in 1-31-23. The filing can be found at www.otcmarkets.com under the ticker symbol "ADHC". Additionally plans to divest of all operating business have been initiated in anticipation of a comprehensive transition of all company operations. Agreements have been reached for a new CEO, a New Advisory Board and a new operating business. Additionally, ADHC management has been advised by litigation counsel that a judicial order cancelling 325 mm shares of common stock is expected imminently. Parties a have agreed to refrain from publicizing any details of these agreements until formal execution has taken place. It is anticipated that all developments should be consummated in April, 2023. ADHC has filed suit in The Eight Judicial Circuit Court, Clark County, Nevada case, Number A-21-843-670, seeking the cancellation of 325,000,000 (325 MM) shares of common stock. On January 6, 2023, the court granted the motion for default and will be issuing the formal order soon. The signed court order granting default judgment is the final legal step before all litigation is resolved. Currently, ADHC capitalization structure is as follows: Shares Outstanding: 1.1 billion Shares Restricted: 600 million Shares in the Float: 504 million GLOBAL CBD PET INDUSTRY OVERVIEW: GLOBAL CBD PET MARKET: $198MM 2022; $248MM 2023; $2 BILLION 2030 ANNUAL GROWTH RATE: 31.8 % COMPOUNDED ANNUAL GROWTH RATE E-COMMERCE SEGMENT: 42% OF REVENUES INDICATION: JOINT PAIN, ANXIETY/STRESS, EPILEPSY, GENERAL HEALTH AND WELLNESS see https://www.grandviewresearch.com/industry-analysis/cannabidiol-pet-market About ADHC: American Diversified Holdings Corporation (OTC: ADHC) is a publicly traded holding company trading under the ticker symbol "ADHC". Investor Contact: Ernest Remo Chairman/CEO EMAIL: ernestremo@san.rr.com Tel: 858-259-4534 TWITTER: @ADHCManagement. This Twitter page is the only official Twitter page for ADHC. Information contained herein includes forward-looking statements. These statements relate to future events or future financial performance, involving known and unknown risks and uncertainties that may cause our actual results to be materially different from the performance or achievements expressed. You should not place undue reliance on these statements since they involve known and unknown risks, in some cases, beyond our control. Contact Details Ernest Remo +1 858-259-4534 ernestremo@san.rr.com Company Website https://rollschoiceadhesive.com/

March 20, 2023 06:30 AM Eastern Daylight Time

News Release

Owlet shares latest technology to keep parents connected with baby's health

Owlet

Owlet CEO and co-founder Kurt Workman joins Proactive's Natalie Stoberman to discuss the company's baby monitoring technology that's available for families to stay connected with their baby's health. Owlet was founded by a team of parents in 2012. Owlet’s digital parenting platform aims to give parents real-time data and insights to help parents feel calmer and more confident. Contact Details Proactive USA +1 347-449-0879 na-editorial@proactiveinvestors.com

March 17, 2023 01:24 PM Eastern Daylight Time

Video

News Release

BioVaxys acquires TAETSoftware to utilize Trial Adverse Events Tracker platform

BioVaxys Technology Corp

BioVaxys CEO James Passin joins Natalie Stoberman from the Proactive newsroom to discuss the company's acquisition of TAETSoftware, a Vancouver-based clinical studies management company engaged in the development and commercialization of the Trial Adverse Events Tracker (TAET) technology platform. Passin says the acquisition of TAETCO provides BioVaxys with a third low-risk near-term revenue generating product, supporting its core business in cancer and viral vaccine development. Contact Details Proactive Canada +1 604-688-8158 na-editorial@proactiveinvestors.com

March 17, 2023 12:08 PM Eastern Daylight Time

Video

News Release

Valeo Pharma sees record quarterly revenue with a triple-digit increase over 1Q 2022

Valeo Pharma Inc.

Valeo Pharma CEO Steve Saviuk joined Steve Darling from Proactive to share news the company had a record quarter in the three months to January 31, 2023, with revenue of $13.2 million, up 210% over 1Q 2022. Saviuk tells Proactive this marks the 5th consecutive quarter of growth for the company, with adjusted gross profit increasing by 178% to $4.2 million from a year earlier. Physicians prescribing Enerzair and Atectura reached 1,583 at the end of the first quarter, 39% growth for the quarter and a 799% increase year-over-year. Total annual Enerzair and Atectura prescriptions surpassed 34,000 at the end of 1Q 2023, up 1,917% year-over-year. Contact Details Proactive Canada +1 604-688-8158 na-editorial@proactiveinvestors.com

March 17, 2023 11:40 AM Eastern Daylight Time

Video

New to The Street Airs its Televised Corporate Interviews on Newsmax TV and The FOX Business Network, Episodes 449 and 450; Broadcastings Begin Saturday, March 18, 2023, at 3:30 PM ET

New To The Street

The Following Corporate interviews will air on Newsmax TV, episode 449, Saturday, March 18, 2023, at 3:30 PM ET, and on the FOX Business Network, episode 450, Monday, March 20, 2023, at 10:30 PM PT. 1). Health Insurance – Health in Tech's interview with Tim Johnson, CEO. 2). E-commerce/ Digital Marketing – Society Pass Incorporated's (NASDAQ: SOPA) ($SOPA) interview with Dennis Nguyen, Founder/CEO/Chairman. 3). Digital Marketing Solutions– Deviate Digital Agency's interview with Jonas Muthoni, Founder/CEO. 4). Sustainable Solutions - The Sustainable Green Team, Ltd.'s (OTCQX: SGTM) ($SGTM) HumiSoil Product Commercial. 5). "Sekur Privacy & Sekur Security Segment -The Weekly Hack" interview with internet privacy expert Mr. Alain Ghiai, CEO, Sekur Private Data, Ltd. (OTCQX: SWISF) (CSE: SKUR) (FRA: GDT0) ( Sekur® ). Tim Johnson, CEO of Health in Tech, sits with New to Street's TV Host Jane King from the Nasdaq MarketSite studio to discuss the Company. As a disruptive innovator in the health insurance industry, Heath in Tech provides technological-based self-funded health insurance solutions for the needs of small businesses. Most businesses in the US have under 100 employees who need comprehensive insurance coverage. Many small businesses have few options for good insurance coverage at costs that can be sustainable. Tim informs viewers as an insuretech Company, he and his team are constantly looking for improvements in cost-effective insurance for small entities. In the Fall of 2022, the Company launched "eDIYBS" (Do it Yourself Benefits System), a web-based software platform that gives a real-time health insurance quote. Insurance brokers, carriers, and other healthcare insurance professionals can log on to the system and shop for the best possible healthcare coverage. A legacy insurance system can take up to 2 weeks or longer for a small business owner to receive a quote; eDIYBS provides quotes within minutes. Approximately $3.5T is spent yearly in the US on health care, and Health in Tech looks for innovations to reduce health coverage costs. The Company has a team of executives with years of experience in the health insurance industry ready to assist small business owners and their healthcare brokers with the best and cheapest insurance. Health In Tech eDIYBS platform continues to see more brokers and carriers signing up. Tim welcomes employers, insurance carriers, and brokers to sign up through the Company's website, www.healthintech.com. The interview will air on Newsmax TV, episode 449, March 18, 2023, 3:30 PM ET and on the FOX Business Network, episode 450, March 20, 2023, 10:30 PM PT. The on-screen QR code is available during the show; download or visit Health in Tech - www.healthintech.com. From the Nasdaq MarketSite studio, New to The Street TV airs Dennis Nguyen, Founder, CEO, and Chairman at Society Pass Incorporated. (NASDAQ: SOPA) ($SOPA) interview with TV Host Jane King. Society Pass is a leading Southeast Asia e-commerce and fintech Company with several business verticals. Dennis tells viewers that 2022 was an excellent year for the Company, with more acquisitions and higher revenue growth from its 6- business verticals - loyalty awards, lifestyle, telecom, travel, food/beverage, and digital media ads. In March 2022, Southeast Asia lifted its Covid restrictions, and SOPA's travel subsidiary NusaTrip, a leading Indonesia-based online travel agency, has seen upward solid growth. Dennis and the travel industry call it "Revenge Travel," where people want to go somewhere after being on lockdown during the Covid crisis. NusasTrip's revenues are up monthly, and travel bookings remain strong. NusaTrip has access to over 500 airlines and over 200,000 hotels to assist customers in bookings. Dennis states that the Company continues to execute its business plan outlined to investors at the time of the Company's IPO. The number of employees has grown from forty-five (45) in 2021 to about two hundred fifty (250) in 2022, and SOPA expects to employ about five hundred (500) in 2023. Women play a significant role in SOPA's growth and success, with over 50% of its personnel being women. SOPA will soon file its US SEC 2022 Annual Report on FORM 10K, providing operational and financial disclosures. The interview will air on Newsmax TV, episode 449, March 18, 2023, 3:30 PM ET and on the FOX Business Network, episode 450, March 20, 2023, 10:30 PM PT. The on-screen QR code is available during the show; download or visit Society Pass Incorporated - https://thesocietypass.com/. New to The Street's TV Host Jane King interviews Jonas Muthoni, CEO/Founder of Deviate Digital Agency (Deviate). From the New York Stock Exchange (NYSE) studio, Jonas explains Deviate's business model and how it assists with many clients in different industries. Many businesses overlook the importance of using the many available digital marketing channels. Jonas and his team explore other digital marketing ideas with clients putting together a comprehensive strategy and creating an effective business plan to achieve maximum digital content exposure for clients' goods/services. Deviate differs from competitors because they partner with clients, using strategies and ideas to get the best social media coverage and digital marketing exposure. With its technology platform, Deviate can provide digital matrix information so a client can see data results. Those results can assist in adjusting methods to get the best possible outcomes for brand awareness and sales generations. Jonas and his team's optimization strategies, website designs /developments, paid ads, and professional social media marketing tools can grow a client's e-commerce footprint for years. The interview will air on Newsmax TV, episode 449, March 18, 2023, 3:30 PM ET and on the FOX Business Network, episode 450, March 20, 2023, 10:30 PM PT. The on-screen QR code is available during the show; download or visit Deviate Digital Agency - https://deviateagency.com/. New to The Street airs The Sustainable Green Team, Ltd.'s (OTCQX: SGTM) ($SGTM) HumiSoil Product Commercial. The onset of modern agricultural methods with the innovation of synthetic fertilizers is destroying soil's natural components. Soil has lost the ability to maintain nutrients and water from the overused non-organic fertilizers. Humus is the main compound of soil, the energy of the ground, which is like a battery storing much-needed nutrients and water for the growth of crops. A depletion of a soil's energy reduces crop yields. The soil cannot regenerate or recharge without humus for future crop yields. A sustainable solution is SGTM's HumiSoil product which uses less water, no fertilizer requirements, and can yield 100% organic vegetables, fruits, and flowers. The product rebuilds soil hydration on a cellular level and keeps CO2 from being released into the atmosphere, creating an organic soil composition that feels and smells very earthy. HumiSoil has a "Zero-Carbon" footprint and works in any climate, soil, and atmospheric conditions as a sustainable organic product. The Earth has a population of about 8 billion people, and sustainability will be the key to future generations' access to sustainable agricultural products to ensure healthy and robust food sources. HumiSoil is now available for gardeners and farmers. The Sustainable Green Team, Ltd. and VRM BioLogik Group have a strategic relationship, and a distribution agreement, whereas SGTM can produce and sell HumiSoil in the USA / Caribbean markets. The HumiSoil product commercial will air on Newsmax TV, episode 449, March 18, 2023, 3:30 PM ET and on the FOX Business Network, episode 450, March 20, 2023, 10:30 PM PT. Viewers can learn more at The Sustainable Green Team, Ltd. - https://www.thesustainablegreenteam.com/. New to The Street re-airs its "Sekur Privacy & Sekur Security Segment – The Weekly Hack " with Alain Ghiai, an internationally acclaimed internet privacy expert and the CEO of Sekur Private Data, Ltd. (OTCQX: SWISF) (CSE: SKUR) (FRA: GDT0). Alain talks with TV Host and Multi-media Journalist Ana Berry about several cybersecurity breaches at GoDaddy. The cPanel access, an open-source code platform used by coders and programmers at GoDaddy, is the possible source of numerous hacks. Hackers accessed the cPanel and installed malware redirecting hosted domains and email accounts. GoDaddy's customers experienced many business disruptions from these cyberattacks. Sekur.com can offer a business and individuals a secure and private e-communication platform. SekurMail, with its SekurSend/SekurReply options, protect both the subscriber and the recipient, even if the recipient is not a Sekur subscriber. Sekur, a closed-loop encrypted military platform, operates on its wholly owned servers in Switzerland and offers a security solution unavailable on those free, open-source Big Tech platforms. A business can migrate its domain onto the Sekur services platform. SekurMail is $7.00 for individuals and $10.00 for a business email, and with PROMO CODE: PRIVACY, subscribers can get an additional 15% off monthly and yearly subscriptions, good for 5-years on uninterrupted subscriptions. With Sekur's enhanced security features, end-users can greatly minimize a possible cybercriminals attack. Sekur Private Data, Ltd. operates its internet platforms and security businesses under the country of Switzerland's very tough privacy laws. It never data mines, never sells data, and never asks for a phone number. The on-screen QR code is available during the show to download more info or visit Sekur Private Data, Ltd. – http://www.Sekur.com. The interview re-airs on Newsmax TV as episode 449, March 18, 2023, 3:30 PM ET and on the FOX Business Network as episode 450, March 20, 2023, 10:30 PM PT. What is your privacy worth? About Health in Tech: Health in Tech is the industry-leading insurtech Company that delivers disruptive innovation and proprietary technology to reimagine everything one needs to know about risk, underwriting, and self-funding, making all processes better, faster, and more efficient for everyone involved. Clients can get a quote for small and medium-sized groups from weeks to minutes. Health in Tech provides all the insurance information available within seconds, delivering clients an all-encompassing "Cradle to Grave" solution. Its technology platform provides immediate access to actionable data and tools, giving efficient and accurate information on health insurance options - www.healthintech.com. About Society Pass Incorporated (NASDAQ: SOPA): Founded in 2018 as a data-driven loyalty, fintech, and e-commerce ecosystem in the fast-growing markets of Vietnam, Indonesia, Philippines, Singapore, and Thailand, which account for more than 80% of the Southeast Asia (SEA) population, and with offices located in Angeles, Bangkok, Ho Chi Minh City, Jakarta, Manila, and Singapore, Society Pass Incorporated ( NASDAQ: SOPA ) is an acquisition-focused holding company operating six interconnected verticals (loyalty, digital media, travel, telecoms, lifestyle, and F&B), which seamlessly connects millions of registered consumers and hundreds of thousands of registered merchants/brands across multiple product and service categories throughout SEA. Society Pass leverages technology to tailor a more personalized experience for customers in the purchase journey and transform the entire SEA retail value chain. SoPa operates Thoughtful Media Group, a Thailand-based, social commerce-focused, premium digital video multi-platform network; NusaTrip, a leading Indonesia-based Online Travel Agency; Gorilla Networks, a Singapore-based, web3-enabled mobile blockchain network operator; Leflair.com, Vietnam's leading lifestyle e-commerce platform; Pushkart.ph, a popular grocery delivery company in the Philippines; Handycart.vn, a leading online restaurant delivery service based in Vietnam; and Mangan.ph, a leading local restaurant delivery service in Philippines - https://thesocietypass.com/. About Deviate Design Agency: Deviate Design Agency is a specialized team with one of the most robust branding, digital marketing, and social media strategies practiced in the entire industry. The Agency corner the market with exclusively learned skill sets known by only a few in the marketing world. Its experts deliver some of the most effective campaigns ranging from global enterprises to today's up-and-coming startup businesses. Deviate Design Agency's seasoned professional marketing, advertising, design, and web experts provide a full spectrum of marketing services, from massive social media presence and strategic planning to designing and developing ads, websites, and print collateral that perform. With all their information, Deviate Design knows what the marketplace responds to and can quickly create a financial lift for their clientele. They seek to get to know their clients and build long-term working relationships - https://deviateagency.com/. About The Sustainable Green Team, Ltd. (OTCQX: SGTM) ($SGTM) The Sustainable Green Team, Ltd. (OTCQX: SGTM) ($SGTM) is an emerging provider of environmentally beneficial solutions for preserving natural resources and the municipal waste and recycling industries. The Company is a wholesale manufacturer and supplier of wood-based mulch and lumber products, primarily in the Midwest, Southeast, and Ohio Valley regions. The Company also provides arbor care and storm recovery services to municipalities, corporations, and consumers, primarily in the southeastern United States. The Company plans to expand its operations through organic growth and strategic acquisitions that are both accretive to earnings and positioned for rapid growth from the resulting synergistic opportunities identified. The Company's customers include governmental, residential, and commercial clients - https://www.thesustainablegreenteam.com/. About VRM BioLogik Group: Since 1987, VRM BioLogik has developed and implemented technological advances globally that catalyze natural reactions, aiding in soil restoration, resolving environmental emergencies, and cleaning through attaining and sustaining ecosystem balance. VRM's agricultural product range works to enhance crop yield while restoring the nutrients in soils naturally. Its cleaner product range naturally removes residues from surfaces that harbor viruses and pathogens. The environmental management product range works to address and amend difficult environmental circumstances, including balancing wastewater, control of odor and organics digestion during emergency spills, and eliminating odors. VRM's livestock product range is a probiotic approach to environmental management in intensive growing situations - https://www.vrm.science/. About Sekur Private Data Ltd. (OTCQX: SWISF) (CSE: SKUR) (FRA: GDT0): Sekur Private Data, Ltd. (OTCQX: SWISF) (CSE: SKUR) (FRA: GDT0) is a cybersecurity and internet privacy provider of Swiss-hosted solutions for secure communications and secure data management. The Company distributes a suite of secure cloud-based storage, disaster recovery, document management, encrypted emails, and secure communication tools. It sells its products through its websites www.sekur.com, approved distributors, and telecommunication companies worldwide. Sekur Private Data, Ltd. serves consumers, businesses, and governments worldwide - https://www.sekurprivatedata.com and https://www.sekur.com; Twitter: @sekurprivate. About New to The Street: New to the Street is an FMW Media production that operates one of the longest-running US and International sponsored and syndicated Nielsen Rated programming television brands, "New to The Street," and its blockchain show, "Exploring The Block." Since 2009, these brands have run biographical interview segment shows across major U.S. television networks. The paid-for-television programming platforms can potentially reach over 540 million homes in the US and international markets. FMW's New to The Street / Newsmax televised broadcasting platform airs its syndication on Saturdays at 3:30 – 4:00 PM ET. FMW is also one of the nation's largest buyers of linear television, long and short-form paid programming - https://www.newsmaxtv.com/Shows/New-to-the-Street & https://www.newtothestreet.com/. Forward-Looking Statements Disclaimer: This press release contains forward-looking statements within Section 27A of the Securities Act of 1933, as amended, and Section 21E of the Securities Exchange Act of 1934. In some cases, you can identify forward-looking statements by the following words: "anticipate," "believe," "continue," "could," "estimate," "expect," "intend," "may," "ongoing," "plan," "potential," "predict," "project," "should," "will," "would," or the negative of these terms or other comparable terminology. However, not all forward-looking statements contain these words. Forward-looking statements are not a guarantee of future performance or results and will not necessarily be accurate indications of the times at which such performance or results are achieved. This press release should be considered in all filings of the Companies contained in the Edgar Archives of the Securities and Exchange Commission at www.sec.gov. Contact Details Business Development New To The Street +1 516-696-5900 support@newtothestreet.com FMW Media Contact Monica Brennan +1 917-330-2564 monica@NewtoTheStreet.com Company Website https://newtothestreet.com/

March 17, 2023 10:42 AM Eastern Daylight Time

Video

NeuroRestorative Illinois Opens Bloomington Location

Sevita

NeuroRestorative, a member of the Sevita family, is celebrating the opening of its NeuroRestorative Academy in Bloomington. This is the sixth Academy location in the U.S., and the third in Illinois. An open house and ribbon cutting event was held on Wednesday, March 15, in partnership with McLean County Chamber of Commerce. NeuroRestorative Academies provide supportive education environments and therapeutic services designed to make learning more accessible to students who have a traumatic brain injury (TBI) and/or behavioral health needs. Students enrolled at the Academy may be facing behavioral or emotional challenges, multiple disabilities, speech and language impairments, or other health impairments, including TBI or neurologic impairment. The new Bloomington location will welcome 25 residential and day students, currently supported by 18 staff members including educators, healthcare professionals (recreational therapists, occupational therapists, etc.), social workers, and residential supervisors. The Academies leverage in-house brain injury rehabilitation and neurological expertise and experience to provide an inclusive, moderately acute setting for children and adolescents who have not found success within traditional school settings, yet do not need the level of care provided in higher-intensity settings such as hospitals and institutions. “For more than 40 years, NeuroRestorative has been responding to the behavioral health needs of Illinois families,” said Jim Para-Cremer, Vice President of Operations for NeuroRestorative. “We are truly delighted that this expansion will allow us to bring our clinical and educational skill and experience to the Bloomington community. Together, we know we can positively impact the lives of children and their families and support each person we serve to live well.” Para-Cremer continued, “As a Licensed and Board-Certified Behavioral Analyst, I know that children who are not successful in a traditional school environment can often find success and gain the skills they need to thrive when provided with the right environment of care and support.” Approach: The Academies provide an evidence-based curriculum that is individualized for each student. A Dynamic Learning Plan draws on personalized and proactive intervention approaches. Personalized supports and services are designed to promote both academic and rehabilitative success, including academic testing and support, medical management, social integration, physical and cognitive rehabilitation, family therapy, emotional and behavioral support, transition living preparation, and overall wellness. Success: Of students who’ve attended a NeuroRestorative Academy program, 93% have transitioned home. Additionally, 80% of those served realized a notable reduction in disability (as measured by the Mayo Portland Total T-Score). Mac is one such student that has found success within the NeuroRestorative Academy program. Coming from a Russian orphanage where he was neglected, Mac has had to fight through various obstacles in his life. He was diagnosed with bipolar disorder at a young age and, before attending NeuroRestorative Academy Chicagoland in Mount Prospect, struggled with processing and containing his emotions. At the Academy, Mac felt comfortable and supported, grew emotionally and behaviorally, and has since graduated high school and begun pursuing his career goals. Learn more: Visit the NeuroRestorative site to watch Mac’s full story, read more successful outcome stories, and find more information about the new NeuroRestorative Academy - Bloomington location. ### About NeuroRestorative NeuroRestorative is a leading provider of subacute and post-acute rehabilitation services for people of all ages with brain and spinal cord injuries and other neurological challenges. In various locations and settings, we offer a continuum of care and community-based programs, including specialized services for children and adolescents, adults, military service members and veterans, injured workers, and the elderly. Our dedicated team of professionals is focused on empowering individuals to achieve their potential through a continuum of outcome-driven, community-based rehabilitation programs and specialized supports. About Sevita Sevita is a leading provider of community-based specialized health care, inspired by our core values of respect, integrity, inclusion and growth. We provide people with quality services and individualized supports that lead to growth and independence, despite the physical, intellectual, or behavioral challenges they face. We’ve made this our mission for more than 50 years. Today our team members continue to innovate and enhance care for the 50,000+ individuals we serve. sevitahealth.com Contact Details Melissa Patricio media@sevitahealth.com Company Website https://sevitahealth.com/

March 17, 2023 09:00 AM Eastern Daylight Time

Image

Healthcare

A Company With Solutions Against Emerging COVID Variants And Other Viral Infections To Combat Future Pandemic Threats

Hong Kong Baptist University-led research unveils cell entry mechanism of SARS-CoV-2 and therapeutic target for COVID-19

Kadimastem Earns FDA Approval of its IND Application For its US Multi-Site Phase IIa Clinical Trial of AstroRx® to Treat ALS

AMERICAN DIVERSIFIED HOLDINGS CORP (OTC: ADHC) REACHES AGREEMENT FOR COMPREHENSIVE TRANSITION OF ALL BUSINESS OPERATIONS

Owlet shares latest technology to keep parents connected with baby's health

BioVaxys acquires TAETSoftware to utilize Trial Adverse Events Tracker platform

Valeo Pharma sees record quarterly revenue with a triple-digit increase over 1Q 2022

New to The Street Airs its Televised Corporate Interviews on Newsmax TV and The FOX Business Network, Episodes 449 and 450; Broadcastings Begin Saturday, March 18, 2023, at 3:30 PM ET

NeuroRestorative Illinois Opens Bloomington Location