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Viral DeFi Memecoin Cutoshi (CUTO) Continues Ecosystem Developments, With Launch of Cutoshi Wallet Website

Cutoshi

The MemeFi token Cutoshi (CUTO) continues to dominate with its blend of meme culture and real DeFi tools and has now launched its Cutoshi Wallet website. The team has made a large advancement. DeFi has become less complicated and more fun according to their goal since its inception. A Fresh Take on DeFi The platform stands out due to its unique capability of merging humor with operational functions. With their wallet launch, they now provide more ease for everyone across the board - from newcomers to seasoned users. The team expressed their goal to create a simple, useful system which both beginners and professionals could use. The new wallet enables users to manage their assets through a straightforward interface that functions for new users and experienced users alike. What You’ll Find in the Cutoshi Wallet You Hold the Keys It’s non-custodial. Your crypto possession remains under your control rather than a centralized entity. Works Across Chains The wallet connects with over 20 blockchains, so moving your tokens between networks won’t be a pain. No Extra Tools Needed Buying and staking? It’s all right there. No need to jump between different apps. More Utility for $CUTO The wallet will have exclusive features available only to users who hold $CUTO. The increased demand for the token will rise as more users join the platform because of this requirement. Strengthening the Cutoshi Ecosystem This wallet is part of a bigger plan. The Cutoshi project continues to develop an ecosystem that combines memes with real utility by working on the Cutoshi Wallet and Cutoshi Swap platform alongside other tools. According to the team, their mission extends beyond riding the popularity of memes. We are creating a system that people can utilize in their quest for financial freedom. Users can register for future notifications about the upcoming swap platform, which will launch shortly. About Cutoshi (CUTO) The Cutoshi MemeFi project delivers user-friendly decentralized finance tools that users can have fun with. Its multi-chain support alongside staking features and token swaps makes cryptocurrency easier to understand and usable for everyone. Want to Dive In? Visit the Swap Platform and Join the Waitlist: Cutoshiwallet.com Main Site: Cutoshi.com Twitter (X): @CutoshiToken Telegram: t.me/cutoshi Media or Partnership Inquiries? 📩 hello@cutoshi.com Cutoshi is a revolutionary meme coin inspired by the Chinese Lucky Cat and Satoshi Nakamoto’s teachings. It’s based on decentralization, privacy, and monetary freedom, embodying the blockchain's original purpose and ethos. Cutoshi has a vision - to introduce more people to cryptocurrencies and bring financial freedom to all who want it. This article is for general info only and isn’t meant as financial advice. Crypto is risky. Always do your own research or talk to a financial advisor before investing. Contact Details Cutoshi Camila support@cutoshi.com Company Website https://cutoshi.com/

April 16, 2025 02:25 PM Eastern Daylight Time

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Trending MemeFi Token Cutoshi (CUTO) Announces New Development, As Cutoshi Swap Website Goes Live

Cutoshi

Cutoshi (CUTO), one of the standout tokens in the MemeFi space, just hit a big milestone — the launch of its new platform, Cutoshi Swap. It’s designed to make trading crypto easier and more private by letting users swap tokens without having to connect a wallet. A Fresh Move for MemeFi Cutoshi has always mixed fun meme culture with real DeFi tools, which helped it grow a strong community. Now with Cutoshi Swap, it’s raising the bar again — offering a new way to trade across chains without the usual friction of wallet connections. The team behind the project said the platform is built to fix problems regular users face. Their words? “We’ve made something simple, with privacy in mind — multi-chain support, no wallet connect needed.” Why Cutoshi Swap Stands Out No Wallet Connection Needed You don’t need to connect your wallet to start swapping — this gives users more control and keeps things private. Supports Multiple Chains The platform isn’t stuck to just one chain. You can move your assets across different blockchains with ease. Very Few Restrictions They’re sticking to decentralization at its core — there’s no long list of banned tokens. That means more coins are usable here. Built for All Levels Whether you’re new to crypto or a DeFi pro, the interface is clean and easy to use. Part of a Bigger Plan This isn’t just a one-off feature. Cutoshi is building an ecosystem. Cutoshi Swap joins a growing list of tools under its belt, all built around transparency, community input, and pushing crypto forward — while keeping that meme vibe alive. One of the team members put it like this: “We think DeFi works best when users don’t have to jump through hoops. It should be simple, direct, and totally yours.” What is Cutoshi (CUTO)? Cutoshi is a MemeFi token — fun on the outside, serious on the inside. It blends meme culture with real utility, offering features like cross-chain transactions, non-custodial trading, and a reward system for its community. Its presale has already attracted people looking to join something that’s equal parts hype and value. Want to Dive In? Visit the Swap Platform and Join the Waitlist: CutoshiSwap.com Main Site: Cutoshi.com Twitter (X): @CutoshiToken Telegram: t.me/cutoshi For press or partnerships: 📧 hello@cutoshi.com Cutoshi is a revolutionary meme coin inspired by the Chinese Lucky Cat and Satoshi Nakamoto’s teachings. It’s founded on the principles of decentralization, privacy, and monetary freedom, embodying the blockchain's original purpose and ethos. Cutoshi has a vision - to introduce more people to cryptocurrencies and bring financial freedom to all who want it. This article is for general info only and isn’t meant as financial advice. Crypto is risky. Always do your own research or talk to a financial advisor before investing. Contact Details Cutoshi Camila Perez support@cutoshi.com Company Website https://cutoshi.com/

April 16, 2025 02:09 PM Eastern Daylight Time

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AGTONOMY’S 3RD GENERATION SOFTWARE PLATFORM REDEFINES REAL-WORLD AUTONOMY ACROSS AGRICULTURE AND TURF

Agtonomy

Agtonomy, a trusted provider of automation and AI solutions, today announced the release of its third-generation Agtonomy Platform™, the most advanced software platform for agriculture and land management. Formerly known as TeleFarmer™, the latest update introduces enhanced fleet intelligence powered by Physical AI, new equipment platform support for mixed fleets, expanded capabilities for diverse crops, turf and open-field operations, and a new name that reflects its growing range of real-world applications across industries. Unlike other autonomous solutions that rely on extensive infrastructure or operator oversight, Agtonomy’s platform delivers true turnkey autonomy—ready to perform from day one without pre-mapping or local base stations. By combining embedded connectivity with vision-based navigation and advanced AI, Agtonomy continues to raise the bar for practical automation in agriculture, enabling broad adoption faster. “There’s a big difference between testing autonomy in controlled environments and deploying it in the real world,” said Tim Bucher, co-founder and CEO of Agtonomy. “Permanent crop autonomy is one of the toughest challenges in agriculture. Our platform has been refined through years of experience navigating narrow rows with high value crops on either side and no margin for error. This latest update takes that expertise further—expanding application while maintaining our commitment to reliability and precision.” Key Features of the Third-Generation Platform 1. Infrastructure-Free Autonomy On the latest Agtonomy-Enabled platforms, integrated cellular and Starlink connectivity, combined with vision-based navigation, eliminates the need for local base stations or manually driven record-and-repeat paths. The result is true autonomous operation from day one, with simplified setup and reduced costs. Where 3D satellite imagery is available, site setup can be completed remotely, eliminating the need for an on-site visit and streamlining deployment. 2. Turf & Open-Field Automation The platform now supports autonomous mowing and task execution across diverse environments such as golf courses, sod farms, pastures, municipal green spaces, and open fields. Agtonomy-Enabled equipment executes these tasks with industry-leading precision, helping reduce labor costs while improving consistency and coverage. 3. Enhanced Fleet Intelligence with Physical AI Agtonomy’s Physical AI enables a single operator to manage 10+ tractors simultaneously—with no practical upper limit. As the system learns from real-world operations, fleet efficiency continues to improve. 4. Expanded Equipment Support The platform now supports mixed-fleet operations across various equipment types, including new equipment integrations like the factory-fit Bobcat CT4045 diesel tractor—a robust solution for demanding autonomous tasks. A Proven Platform for the Real World As Agtonomy enters this next phase of scale and adoption, the company remains focused on what matters most: making automation truly usable. Backed by years of field experience in the most unforgiving environments, the platform is not only smart and scalable, but deeply practical. “This update is all about removing barriers for operators,” said Nic Fischer, head of software at Agtonomy. “No base stations, no complicated mapping—just tap a few buttons and let your equipment do the work autonomously. Its practical autonomy for all operators day one.” With a flexible platform that adapts to different terrains, tasks, and equipment, Agtonomy is empowering operators to do more—with less effort, less complexity, and the precision today’s operations demand. About Agtonomy: Agtonomy is a software and AI services company bringing intelligent automation to agriculture, turf, and land maintenance. Its platform, embedded in commercial equipment through leading OEM partnerships, delivers real-world automation proven in the most complex operating environments. Agtonomy helps customers work more efficiently, safely, and sustainably—without sacrificing precision or control. Learn more or request a demo, visit www.agtonomy.com or follow us on LinkedIn and YouTube. Contact Details AgTech PR for Agtonomy Jennifer Goldston jennifer@agtechpr.com Company Website https://www.agtonomy.com/

April 16, 2025 09:00 AM Central Daylight Time

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Messari Reports Strong Q1 for TRON with Record Revenue, $19B Daily USDT Volume

TRON DAO

Geneva, Switzerland – April 16, 2025 – Messari, a leading provider of digital asset market intelligence products, released a research report highlighting the TRON network’s significant advancements in blockchain activity, ecosystem expansion, and innovation throughout Q1 2025. This report emphasizes TRON’s growing role in decentralized finance (DeFi) and stablecoin adoption, showcasing its robust technical infrastructure, scalability, and high user engagement. State of TRON Q1 2025 Messari’s State of TRON Q1 2025 report provided an in-depth analysis of the network’s exceptional performance in the first quarter of 2025. Their insights emphasized TRON’s operational efficiency, supported by its Delegated Proof-of-Stake (DPoS) consensus mechanism and scalable architecture. The TRON Network experienced positive growth across many key metrics, including a 2.7% QoQ increase in revenue to $760.2 million, an all-time high for the network. Key Insights from Messari: Ecosystem development: Collaborations with Wintermute, T3 FCU, Kiln, and Nansen showcased ecosystem growth in Q1. Technical upgrades: In Q1 the TRON developer community introduced Smart Wallets with advanced features like energy sharing and zero account activation costs, as well as announced gas-free USDT transfers on TRON. Stablecoin usage: Remains strong, with $65.7 billion (+13.9% QoQ) USDT on the TRON network. The average daily USDT transfer volume increased by 3.3% QoQ, reaching $19 billion. TRON continues implementing strategies to grow its ecosystem, with initiatives such as The T3 Financial Crime Unit (T3 FCU), a joint effort by TRON, Tether, and TRM Labs. In Q1, T3 announced it had frozen over $126 million in criminal assets since its launch in August 2024. Read the full Messari report here. About TRON DAO TRON DAO is a community-governed DAO dedicated to accelerating the decentralization of the internet via blockchain technology and dApps. Founded in September 2017 by H.E. Justin Sun, the TRON blockchain has experienced significant growth since its MainNet launch in May 2018. Until recently, TRON hosted the largest circulating supply of USD Tether (USDT) stablecoin, exceeding $60 billion. As of April 2025, the TRON blockchain has recorded over 300 million in total user accounts, more than 10 billion in total transactions, and over $20 billion in total value locked (TVL), based on TRONSCAN. TRONNetwork | TRONDAO | X | YouTube | Telegram | Discord | Reddit | GitHub | Medium | Forum Media Contact Yeweon Park press@tron.network Contact Details Yeweon Park press@tron.network Company Website https://trondao.org/

April 16, 2025 09:47 AM Eastern Daylight Time

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Kripton selects TRON and Tether to Drive Cryptocurrency Adoption and Financial Inclusion in Argentina

Kripton

Buenos Aires, Argentina – April 15, 2025 – Kripton, a leading e-commerce platform in Argentina, announced today a comprehensive strategic alliance with TRON DAO, the community-governed DAO dedicated to accelerating the decentralization of the internet through blockchain technology and decentralized applications (dApps). Together, they will launch initiatives aimed at revolutionizing digital payments and expanding financial inclusion in the Argentine market. In this multi-faceted collaboration, more than 2,000 merchants working with Kripton will adopt USDT (Tether USD) as their premier digital dollar, enabling secure, efficient, and subsidized payments on the TRON network. TRON will subsidize all transaction fees between Kripton and its users, significantly reducing costs and improving efficiency for consumers and merchants. Additionally, the strategic alliance will offer interest-free microloans to central market workers for the purchase of carts and work apparel, promoting economic growth and financial inclusion. The microloan initiative is projected to generate approximately 110,000 transactions and $2 million in volume over an 18-month period. Funding of the microloans will be derived from transactions conducted by market workers using USDT balances on the TRON network at Kripton-integrated businesses. "We are excited to have TRON join this initiative we've been working on," said Juan Pablo Moreno, CEO of Kripton. "Given that TRON is the network with the highest number of USDT transactions and has been actively working with the community for the longest time, we are confident that this integration will benefit our users and contribute to the growth of the crypto ecosystem in Argentina." This strategic alliance connects ongoing collaborative efforts between Kripton, TRON, Tether, and civil organizations that promote the use of Bitcoin and cryptocurrencies in Argentina. "TRON is committed to promoting the use of blockchain and cryptocurrencies in the region," said Sam Elfarra, Community Spokesperson at the TRON DAO. "This collaboration with Kripton and Tether is an important step toward the mass adoption of blockchain technologies in Argentina and the region." About TRON DAO TRON DAO is a community-governed DAO dedicated to accelerating the decentralization of the internet via blockchain technology and dApps. Founded in September 2017 by H.E. Justin Sun, the TRON blockchain has experienced significant growth since its MainNet launch in May 2018. Until recently, TRON hosted the largest circulating supply of USD Tether (USDT) stablecoin, exceeding $60 billion. As of April 2025, the TRON blockchain has recorded over 299 million in total user accounts, more than 10 billion in total transactions, and over $18 billion in total value locked (TVL), based on TRONSCAN. TRONNetwork | TRONDAO | X | YouTube | Telegram | Discord | Reddit | GitHub | Medium | Forum Media Contact Yeweon Park press@tron.network About Kripton Kripton.la is the leading provider of payment processors for merchants in Latin America and a retail service provider for cryptocurrency users. Since 2019, they have been developing a community seeking to apply the Bitcoin philosophy to the retail industry and decentralize it. Media Contact Melisa Diaz Faverin melifaverin@kriptonmarket.com Contact Details Melisa Diaz Faverin melifaverin@kriptonmarket.com

April 15, 2025 02:00 PM Eastern Daylight Time

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Comcast RISE to Award $3 Million in Grants to 100 Local Small Businesses in the Wasatch Front

Comcast Utah

Today, Comcast announced that it will award comprehensive grant packages to 100 small business owners in the Wasatch Front. These grants are part of a program to support the growth of small businesses and entrepreneurs committed to uplifting their local communities. Each grant package includes a robust array of support, including a technology makeover, creative production, a media schedule, educational resources, a $5,000 monetary grant, and business consultation services. Between May 1 and May 31, eligible small businesses in Bluffdale, City of Draper, Herriman City, Riverton, Sandy City, South Jordan, City of West Jordan, and White City can apply for the Comcast RISE program at www.ComcastRISE.com. Grant packages will include: TECHNOLOGY MAKEOVER - Computer equipment and Internet, Voice, and Cybersecurity services for 12 months. (Taxes and other fees may apply for tech makeover services.) CREATIVE PRODUCTION & MEDIA - Professionally produced 30-second TV commercial, plus a media strategy consultation and a 180-day linear media schedule. (Taxes and other fees may apply for production and media services.) EDUCATION RESOURCES - 12-month access to online entrepreneurship courses, learning modules and resources for small business owners. MONETARY GRANT - $5,000 monetary grant. COACHING SESSIONS - Business assessment and coaching that provides business owners with recommendations on how to help grow their businesses. Wasatch Front, Utah is one of five regions where 100 local businesses will receive Comcast RISE grants, including Boston, Grand Rapids, Mich., Nashville, Tenn., and Seattle. The 500 total recipients will join the 14,000 entrepreneurs nationwide who have been supported through Comcast RISE since the program launched in 2020. “Among the many things we all love about Utah is our vibrant small businesses and Comcast’s commitment to supporting them,” said J.D. Keller, senior vice president of Comcast’s Mountain West Region. “The Comcast RISE program will deliver innovative and impactful resources that will make a lasting impact on small businesses in Utah. Supporting small businesses is crucial for economic development and ensuring that the backbone of our communities can thrive.” “The Comcast RISE program was everything I needed during a time of uncertainty and loss," said Tenisha Hicks, owner of Isha Recovery and Sculpt and former Comcast RISE recipient. “Having a way to help boost my business and ensure that patients can find me was a blessing, one that keeps giving to this day. I am so grateful for the Comcast RISE program and hope that it can help other businesses in the future because it certainly helped mine." Comcast RISE is part of Project UP, the company’s comprehensive initiative to create digital opportunity and help build a future of unlimited possibilities. More information on eligibility requirements and details on how to apply are available at www.ComcastRISE.com. Comcast Corporation (Nasdaq: CMCSA) is a global media and technology company. From the connectivity and platforms we provide, to the content and experiences we create, our businesses reach hundreds of millions of customers, viewers, and guests worldwide. We deliver world-class broadband, wireless, and video through Xfinity, Comcast Business, and Sky; produce, distribute, and stream leading entertainment, sports, and news through brands including NBC, Telemundo, Universal, Peacock, and Sky; and bring incredible theme parks and attractions to life through Universal Destinations & Experiences. Visit www.comcastcorporation.com for more information. Contact Details Deneiva Knight +1 520-345-9792 deneiva_knight@comcast.com Company Website https://utah.comcast.com/

April 14, 2025 02:00 PM Mountain Daylight Time

XLF Fund Opens Doors to U.S. Financial Sector

Select Sector SPDR

The Financials Select Sector SPDR Fund ( XLF ) stands as an option for investors seeking exposure to the dynamic U.S. financial sector. By incorporating a broad range of financial stocks from the S&P 500, XLF provides a streamlined entry point to one of the most pivotal segments of the economy. A Balanced Fund XLF employs a modified market capitalization-weighted index strategy, offering investors a balanced approach to financial sector investment. This methodology focuses on well-established, large-cap companies while also capturing sub-sectors such as banking, insurance, credit services, and capital markets. Notable Holdings* Include: Berkshire Hathaway B – 13.98% JP Morgan Chase – 9.82% Visa A – 8.65% Mastercard A – 6.39% Bank of America– 3.96% Wells Fargo – 3.38% Goldman Sachs – 2.44% Progressive – 2.37% S&P Global – 2.29% American Express– 2.14% This mix of holdings provides exposure to various segments of the financial sector. Accessibility for All Investors For investors aiming to enter the financial sector without the complexity of picking individual stocks, XLF presents an accessible and straightforward option. By pooling a collection of financial stocks, the fund eliminates the heavy lifting involved in individual stock selection, making it a practical choice for both seasoned and new investors. A Seamless Gateway to the Financial Sector XLF is engineered to enable investors to take advantage of the financial sector’s critical role in the economy. With its portfolio focused on the financial components of the S&P 500, it provides exposure to various aspects of the financial sector. For more information about the Financial Select Sector SPDR Fund (XLF) and how it may serve your investment needs, please visit our website @ sectorspdrs.com. XLF offers an efficient and accessible pathway into the U.S. financial sector. DISCLAIMER: This is a work of research and should not be taken as investment or financial advice. Therefore, Select Sector SPDRs or the publisher is not liable for any decision made based on the publication. About the Company: Select Sector SPDR ETFs offer flexibility and customization opportunities. Many investors have similar outlooks, but no two are exactly alike. Select Sector SPDR ETFs let investors select the sectors that best meet their investment goals. *Holdings, Weightings & Assets as of 3/31/25 subject to change DISCLOSURES The S&P 500 Index is an unmanaged index of 500 common stocks that is generally considered representative of the U.S. stock market. The index is heavily weighted toward stocks with large market capitalizations and represents approximately two-thirds of the total market value of all domestic common stocks. The S&P 500 Index figures do not reflect any fees, expenses or taxes. An investor should consider investment objectives, risks, fees and expenses before investing. One may not invest directly in an index. Transparent ETFs provide daily disclosure of portfolio holdings and weightings All ETFs are subject to risk, including loss of principal. Sector ETF products are also subject to sector risk and nondiversification risk, which generally will result in greater price fluctuations than the overall market. Diversification does not eliminate risk. An investor should consider investment objectives, risks, charges and expenses carefully before investing. To obtain a prospectus, which contains this and other information, call 1-866-SECTOR-ETF (732-8673) or visit www.sectorspdrs.com. Read the prospectus carefully before investing. ALPS Portfolio Solutions Distributor, Inc., a registered broker-dealer, is distributor for the Select Sector SPDR Trust. Media Contact: Company: Select Sector SPDRs Contact: Dan Dolan* Address: 1290 Broadway, Suite 1000, Denver, CO 80203 Country: United States Email: dan.dolan@sectorspdrs.com Website: https://www.sectorspdrs.com/ *Dan Dolan is a Registered Representative of ALPS Portfolio Solutions Distributor, Inc. ALPS Portfolio Solutions Distributor, Inc., a registered broker-dealer, is the distributor for the Select Sector SPDR Trust. SEL008350 EXP 6/30/25 Contact Details Dan Dolan +1 203-935-8103 dan.dolan@sectorspdrs.com Company Website https://www.sectorspdrs.com/

April 11, 2025 05:00 AM Eastern Daylight Time

Timeless Elegance from Lake Como: Elizabetta Showcases Handcrafted Luxury Scarves and Accessories Made in Italy

Rev Up Marketers

Elizabetta, a luxury fashion brand based in the heart of Italy's famed textile region, is redefining timeless style with its exclusive line of handcrafted scarves, shawls, ties, ascots, neckerchiefs, and pocket squares for both women and men. Founded by Francesca Dinardo, Elizabetta is committed to preserving the tradition of fine Italian craftsmanship while offering unique designs that speak to modern sophistication. Each piece in the Elizabetta collection is 100% handmade in Italy, using only the finest silk and wool sourced from ethical, family-run mills. From the drawing table to the final stitch, every product reflects the meticulous attention to detail and passion for excellence that defines Italian artisanal heritage. “ We believe in slow fashion and sustainable luxury, ” says founder Francesca Dinardo. “Our mission is to create beautiful, lasting pieces that honor the traditions of Italian craftsmanship while offering something truly distinctive for our customers around the world.” Designed in-house and inspired by Italian art, history, and culture, Elizabetta’s accessories stand apart for their originality and exclusivity. Limited production runs ensure that each item remains a rare, wearable work of art — not a mass-produced trend. About Elizabetta The Elizabetta brand is a celebration of elegance, individuality, and heritage, appealing to discerning customers who appreciate authenticity and refined design. Whether it’s a silk ascot that elevates formal attire or a wool scarf that adds a touch of class to everyday wear, Elizabetta offers luxury accessories that make a lasting impression. To explore the full collection, visit: https://elizabetta.net/ For media inquiries or collaboration requests, please contact: Francesca Dinardo Email: support@elizabetta.net Location: Lake Como, Italy Contact Details Elizabetta Francesca Dinardo support@elizabetta.net Company Website https://elizabetta.net/

April 10, 2025 09:05 AM Eastern Daylight Time

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Palatin Technologies Scores Triple Win with Breakthrough Results in Obesity, Colitis, and Kidney Disease

Global Markets News

Completion of Phase 2 Obesity Study With MC4R Bremelanotide Plus GLP-1/GIP Tirzepatide Palatin Announces Positive Phase IIb BREAKOUT Study Results in Patients with Type 2 Diabetic Nephropathy Palatin Announces Completion of Patient Enrollment in Phase 2 Study of Orally Administered Melanocortin Agonist PL8177 in Ulcerative Colitis Palatin Technologies (NYSE American: PTN)* is on a remarkable winning streak, reporting positive clinical results across three major diseases in just the past two weeks. The company's latest victory came today with promising data in diabetic kidney disease presented at the National Kidney Foundation Spring Meeting in Boston. "The positive results from our Phase 2b study evaluating a melanocortin agonist in patients with diabetic Type 2 nephropathy represents our third major clinical milestone across distinct therapeutic areas," said Carl Spana, Ph.D., President and CEO of Palatin. "These results, along with previously announced positive topline data from our Phase 2 obesity and ulcerative colitis studies, and the advancement of our Phase 3 dry eye disease program, demonstrate the breadth and robustness of our melanocortin platform." In the six-month BREAKOUT study, patients with Type 2 diabetic nephropathy showed significant improvements in kidney function after treatment with bremelanotide, a melanocortin agonist. Seventy-one percent of patients achieved meaningful reductions in protein levels in urine and maintained or improved their glomerular filtration rate—both critical markers of kidney health. This latest success caps an impressive series of announcements. On March 31, Palatin reported that its Phase 2 obesity study met its primary endpoint with highly statistically significant results. The co-administered group had a 4.4% reduction in weight compared to 1.6% for the placebo group (p<0.0001). Notably, the company's MC4R agonist appeared to prevent weight regain after tirzepatide discontinuation, potentially addressing one of the biggest challenges in obesity treatment. "This study provides compelling evidence that combining an MC4R agonist with a GLP-1/GIP compound creates a synergistic effect on weight loss," said Jesse Richards, DO, of Oklahoma State University College of Osteopathic Medicine, as quoted in Palatin's press release. "With a critical need for diverse weight loss solutions, this approach offers a promising improvement to GLP-1/GIP monotherapy, particularly for those who struggle with tolerability at high doses." Just days earlier, Palatin announced breakthrough results in ulcerative colitis. Their PL8177 treatment demonstrated clinical response in 78% of treated patients versus 33% on placebo (p<0.005), with clinical remission achieved in 33% of PL8177-treated patients versus 0% on placebo. "We are thrilled with the positive results in this study, especially the meaningful and high rates of achievement for clinical remission and clinical response," Dr. Spana stated in the announcement. "These endpoints align with the FDA's recommended primary and key secondary endpoints for evaluating efficacy in UC clinical trials." The potential market impact of these developments is substantial. Palatin's approach to obesity treatment appears particularly timely as Rhythm Pharmaceuticals just reported successful Phase 3 results for setmelanotide in hypothalamic obesity, showing a -19.8% placebo-adjusted BMI reduction. The two companies represent the only players actively developing MC4R-targeted therapies for obesity conditions. Adding to Palatin's momentum, the FDA recently granted "orphan drug" designation to PL7737, the company's oral melanocortin-4 receptor agonist, for leptin receptor deficiency obesity. This designation provides incentives including tax credits for clinical trials and potential market exclusivity. According to Dr. Spana, the company is advancing discussions with multiple pharmaceutical companies for potential licensing deals. "Several major pharmaceutical companies have shown strong interest in our UC program," he stated in the March 28 press release, "and we believe these positive Phase 2 results in PL8177 treated patients, for the critical efficacy endpoints of both clinical remission and clinical response, could help solidify a potential licensing deal." With multiple clinical successes driving interest in its technology platform across billion-dollar markets including obesity, ulcerative colitis, and kidney disease, Palatin appears to be validating its scientific approach as analysts at H.C. Wainwright maintain a $7 price target on the stock. Recent Palatin Technologies News Highlights: Completion of Phase 2 Obesity Study With MC4R Bremelanotide Plus GLP-1/GIP Tirzepatide Palatin Announces Positive Phase IIb BREAKOUT Study Results in Patients with Type 2 Diabetic Nephropathy Palatin Announces Completion of Patient Enrollment in Phase 2 Study of Orally Administered Melanocortin Agonist PL8177 in Ulcerative Colitis *DISCLAIMER: This alert is published by Wall Street Wire. Wall Street Wire does not provide financial or investment advice, and our content does not represent an offer to buy or sell securities. Wall Street Wire is a promotional content brand and its operators are not registered brokers, dealers, or investment advisers. This alert contains and is a form of paid promotional content for to Palatin Technologies and was produced as part of their paid subscription to Wall Street Wire’s distribution and promotional content services. This alert has not been reviewed or approved by Palatin Technologies prior to publication. Please review the full disclaimers and compensation disclosures here: redditwire.com/terms Contact Details WALL STREET WIRE | NEWS News Coverage media.globalmarkets@gmail.com

April 10, 2025 08:37 AM Eastern Daylight Time

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